The investigation of cytotoxic effects of Cinnamomum zeylanicum on human breast cancer cell line (MCF-7)

Cytotoxicity Effect of Cladribine on the MCF-7 Human Breast Cancer Cell Line

Cladribine, an analogue of deoxyadenosine, is highly toxic for both non-dividing and proliferating cells and has shown activity in the treatment of several malignancies. Therefore, the aim of the present study is to investigate the cytotoxicity effect of cladribine (2-CdA) on the breast cancer cell line, MCF-7 (estrogen receptor positive, ER+). MTT assay, annexin V-Fluorescein/PI and Hoechst 33...

evaluation of rheum turkestanicum janischew. root cytotoxic effects on human breast cancer cell line (mcf-7)

The Activity of Sirtuin 1 in MCF-7 Breast Cancer Cell Line: The Effects of Visfatin

Background & Objectives: Breast cancer is the most common cancer and the second leading cause of cancer deaths among women. Obesity, hormones, and growth factors are the risk factors for this kind of cancer. One of the changes observed in patients suffering from breast cancer is the elevated Visfatin or nicotinamide phosphoribosyl transferase (NAMPT) in their tumor tissues and blood. The increa...

Evaluation of anticancer effect of hydroalcoholic extract of Stachys setifera on MCF-7 human breast cancer cell line

Abstract: Background and Aim: Breast cancer is the most common cancer among women. Given that plant compounds have been used to treat cancer for centuries. Despite some reports of antitumor effects on some species of this genus, the anticancer activity of Stachys setifera has not yet been reported. The aim of this study was to investigate the cytotoxic effect of hydroalcoholic extract of Stachy...

Cytotoxic effects of grape (Vitis vinifera, Rishbaba) seed extract on human breast cancer cell line (MCF-7) and its interaction with anticancer drug doxorobicin

Abstract: Introduction: Cancer, a fatal disease, is the second leading cause of death reason exceeded only by cardiovascular disease. Breast cancer is common well known cancers in woman and is the second leading cause of death after lung cancer. In recent years researchers have focused on diet based on herbal medicine for the prevention and treatment of certain types of cancer. Methods: In th...